the relationship between physical factors (wrist ratio) and electrophysiologic factors of median nerve in carpal tunnel syndrome in women

carpal tunnel syndrome (cts) is considered by researchers because of its high prevalence, and several studies have been done to find the causes and factors which increase the chance for the syndrome. these studies have shown relationships between this syndrome with some physical parameters like wrist dimensions, weight and systemic conditions. there is no investigation on risk factors in cts in our country. so the main goal of this research is to find and introduce predisposing factors for carpal tunnel syndrome. methods: seventy patients and 33 controls 22 to 70 years old were studied. standard methods for median and ulnar nerve studies were used and questionnaires included physical measurements, history of diseases and personal information were completed for each person. results: patients had higher wrist ratio (mean difference, 0.0267, p<0.001), weight (mean difference: 6.098, p<0.001) and body mass index (mean difference: 3.376, p<0.001). regression analysis showed strong positive relation between wrist ratio and median latencies. the strongest correlation was found between wrist ratio and median minus ulnar distal sensory latencies (y2=0.4014, p<0.0001). no relation was found between weight and body mass index with median latencies. seventy-nine percent of patients and 48.5% of controls had wrist ratio of 0.7 or greater (p<0.05). seventy-two percent of patients with repetetive hand activities and 78% with associated conditions had wrist ratio of 0.7 or greater. seventy-six percent had wrist ratio less than 0.7. no relationship was found between obesity, diabetes, thyroid disorders, rheumatoid arthritis, taking oral contraceptive, hysterectomy, oophorectomy, menopause and repetetive hand activities with involvement of carpal tunnel syndrome. discussion: wrist dimensions seem to be an important predictor for carpal tunnel syndrome also in patients with associated conditions. if individuals with squarer wrists are involved in special conditions, they may show symptoms of the syndrom. carpal tunnel syndrome is caused by many factors but wrist dimensions seem to be a predisposing factor and provides an explanation for bilateral involvement or familial occurrence of it.